Uninvestigated dyspepsia and related risk factors in college students

Authors

DOI:

https://doi.org/10.53732/rccsalud/2024.e6131

Keywords:

dyspepsia, helicobacter pylori, gastroenterology

Abstract

Introduction. Uninvestigated dyspepsia is a syndrome characterized by a feeling of fullness, epigastric discomfort, nausea, among other symptoms, whether recurrent or isolated episodes, for which an endoscopy has not been performed to determine the etiology. For clinical diagnosis, the Rome IV criteria are used. Material and Methods. A cross-sectional descriptive observational study. Students from the preclinical cycle of the Universidad del Pacífico were subjected to the OnSite H. Pylori Ab Combo Rapid Test diagnostic test, from CTK Biotech inc, consisting in the chromatographic immunoassay technique to qualitatively detect the presence of antibodies in the blood. The students filled out a questionnaire on symptoms and risk factors to acquire dyspepsia. Results. A total of 156 students were studied with an average age of 22.1 years, 65% female, 55,1% from the Central department. The prevalence of uninvestigated dyspepsia was 32,7% and of anti- H. Pylori antibodies 14%; 13% claimed to be a smoker of at least 1 cigarette/day, 71% reported drinking alcohol, and 45% consuming NSAIDs with a high frequency. Conclusion. The prevalence of uninvestigated Dyspepsia is high and it would be imperative to assign a cause or categorize it as functional dyspepsia in order to use therapeutic measures. It is also important to identify and control possible risk factors for the pathology.

References

Talledo-Ulfea L, Buitragoc OD, Filorioe Y, Casanovaf F, Camposg L, Cortésh F, et al. Factores asociados a dispepsia no investigada en estudiantes de 4 facultades de medicina de Latinoamérica: estudio multicéntrico. Rev Gastroenterol México. 2018;83(3):215–22. http://dx.doi.org/10.1016/j.rgmx.2017.05.009

Ford AC, Mahadeva S, Carbone MF, Lacy BE, Talley NJ. Functional dyspepsia. Lancet. 2020. 21;396(10263):1689-1702. http://dx.doi.org/10.1016/S0140-6736(20)30469-4

Madisch A, Andresen V, Enck P, Labenz J, Frieling T, Schemann M. The Diagnosis and Treatment of Functional Dyspepsia. Dtsch Arztebl Int. 2018;115(13):222-232. https://pubmed.ncbi.nlm.nih.gov/29669681/

Pérez-Grueso Macías MJ, Valle Muñoz J, Gonzãlez De Frutos C, Artaza Varasa T, Rodríguez-Merlo R, Alcántara Torres M, et al. Características clinicopatológicas de la dispepsia no investigada en España. Gastroenterol Hepatol. 2007;30(1):1–6. https://doi.org/10.1157/13097442

Sayuk GS, Gyawali CP. Functional Dyspepsia: Diagnostic and Therapeutic Approaches. Drugs. 2020;80(13):1319-1336. http://dx.doi.org/10.1007/s40265-020-01362-4

Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, et al. Gastroduodenal disorders. Gastroenterology. 2016;150(6):1380–92. http://dx.doi.org/10.1053/j.gastro.2016.02.011

Sebastián Domingo, JJ. The new Rome criteria (IV) of functional digestive disorders in clinical practice. Medicina Clínica (English Edition). 2017;148(10):464–468. https://doi.org/10.1016/J.MEDCLE.2016.12.070

Caballero-Mateos, AM, Redondo-Cerezo E. Dispepsia, dispepsia funcional y criterios de Roma IV. Rev. esp. enferm. dig. 2018;110(8):530-531. https://dx.doi.org/10.17235/reed.2018.5599/2018

Oustamanolakis P, Tack J. Dyspepsia: Organic versus functional. J Clin Gastroenterol. 2012;46(3):175–90. https://journals.lww.com/jcge/fulltext/2012/03000/dyspepsia__organic_versus_functional.3.aspx

Nasseri-Moghaddam S, Mousavian AH, Kasaeian A, Kanno T, Yuan Y, Ford AC, et al. What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2023;21(7):1739-1749.e2. https://dx.doi.org/10.1016/j.cgh.2022.05.041

Walker MM, Talley NJ. Functional Dyspepsia in the Elderly. Curr Gastroenterol Rep. 2019;21(54). https://dx.doi.org/10.1007/s11894-019-0722-5

Caballero M, Vera E, Aynaguano L, Jara ML, Villacís E, Serrano A, et al. La Frecuencia y caracterización del cáncer gástrico en pacientes con dispepsia en el servicio de gastroenterología del htmc del iess de guayaquil. REVISTA CYA. 2023;2(1). https://revista.htmc.gob.ec/ojs-3.3.0-10/index.php/hetmc/article/view/28

Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015;64(7):1049-57. https://dx.doi.org/10.1136/gutjnl-2014-307843

Lacy BE, Weiser KT, Kennedy AT, Crowell MD, Talley NJ. Functional dyspepsia: the economic impact to patients. Aliment Pharmacol Ther. 2013;38(2):170-7. https://europepmc.org/article/MED/23725230

Lúquez Mindiola A, Otero RW, Schmulson M. Enfoque diagnóstico y terapéutico de dispepsia y dispepsia funcional: ¿qué hay nuevo en el 2019?. Rev. gastroenterol. Perú. 2019; 39(2):141-152. http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1022-51292019000200009&lng=es.

Khoder G, Muhammad JS, Mahmoud I, Soliman SSM, Burucoa C. Prevalence of Helicobacter pylori and Its Associated Factors among Healthy Asymptomatic Residents in the United Arab Emirates. Pathogens. 2019;8(2):44. https://dx.doi.org/10.3390/pathogens8020044

Wang YK, Kuo FC, Liu CJ, Wu MC, Shih HY, Wang SS, et al. Diagnosis of Helicobacter pylori infection: Current options and developments. World J Gastroenterol. 2015;21(40):11221-35. https://dx.doi.org/10.3748/wjg.v21.i40.11221

Breckan RK, Paulssen EJ, Asfeldt AM, Kvamme JM, Straume B, Florholmen J. The All-Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population-Based Study. Helicobacter. 2016;21(6):586-595. https://pubmed.ncbi.nlm.nih.gov/27172105/

Rodríguez-García JL, Carmona-Sánchez R. Functional dyspepsia and dyspepsia associated with Helicobacter pylori infection: Do they have different clinical characteristics? Revista de Gastroenterología de México. 2016;81(3):126–133. https://doi.org/10.1016/j.rgmxen.2016.06.017

Burucoa C, Axon A. Epidemiology of Helicobacter pylori infection. Helicobacter. 2017;22 Suppl 1. https://doi.org/10.1111/hel.12403

Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Neurogastroenterology. 2015; 64(7):1049-57. https://doi.org/10.1136/gutjnl-2014-307843

Published

2024-02-15

How to Cite

Insfran Mendez, G., & Ruiz Diaz, S. (2024). Uninvestigated dyspepsia and related risk factors in college students. Revista científica Ciencias De La Salud, 6, 01–08. https://doi.org/10.53732/rccsalud/2024.e6131