Exercise as treatment for the management of cancer-associated fatigue
DOI:
https://doi.org/10.53732/rccsalud/04.02.2022.95Keywords:
Fatigue, exercise, cancerAbstract
Introduction: Fatigue is a subjective and permanent perception of physical, emotional and/or cognitive fatigue. Highlighting that it is worth mentioning that age is a risk factor for developing cancer and therefore fatigue associated with this disease. Our objective was to determine what are the benefits of exercise in the management of fatigue associated with cancer in adults. Materials and Methods: A systematic review was performed according to the Cochrane statement and with a search in EBSCO, PUBMED, MEDLINE, EMBASE, SCIELO and DOAJ. The methodological quality was made using PRISMA, PICO and PEDro. Scientific articles were used between January 2009 to June 2019. Objective: To determine the benefits of exercise in managing cancer-associated fatigue in adults. Results: Twenty-four clinical studies plus 11 meta-analyzes were included. Exercise was shown to reduce cancer-related fatigue, and the most effective exercises in reducing fatigue in adults with cancer were aerobic exercise, resistance training, and the combination of aerobic and resistance exercise in cancer patients. Conclusions: Aerobic and resistance exercise in combination has been shown to be effective and should be considered part of treatment to decrease cancer-related fatigue in adult patients.
References
Barrios E, Garau M. Cáncer: magnitud del problema en el mundo y en Uruguay, aspectos epidemiológicos. AnFaMed. 2017;4(1):9-46. 10.25184/anfamed2017.4.1.2
Flores D. Envejecimiento y cáncer. Rev Cl EMedi UCR. 2017;7(3):11-16. 10.15517/RC_UCR-HSJD.V7I3.30017
Meneses J, González E, Correa E, et al. Efectividad del ejercicio físico en la fatiga de pacientes con cáncer durante el tratamiento activo: revisión sistemática y metaanálisis. Cad. Saúde Pública. 2015; 31(4):667–681. 10.1590/0102-311X00114414
Vargas C, Uclés V, González J, et al. Síndrome de fatiga relacionado con cáncer. Rev Cl EMed. 2015; 5(4):32-38. 10.15517/RC_UCR-HSJD.V5I4.20774
Uclés V, Espinoza R. Prescripción del ejercicio en el paciente con cáncer. Rev Cl EMed. 2017; 7(2):11-18. 10.15517/RC_UCR-HSJD.V7I2.29142
Ramírez K, Acevedo F, Herrera M, et al. Actividad física y cáncer de mama: un tratamiento dirigido. Rev. Med. Chile. 2017; 145(1):75-84. 10.4067/S0034-98872017000100011
Schmidt ME, Wiskemann J, Armbrust P, Schneeweiss A, Ulrich CM, Steindorf K. Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: A randomized controlled trial. Int J Cancer. 2015;137(2):471-480. 10.1002/ijc.29383
Saz P. Por qué recetar ejercicio en pacientes diagnosticados de cáncer. Medicina naturista. 2016; 10(1):10-14. https://dialnet.unirioja.es/servlet/articulo?codigo=5302162
Urrútia G, Bonfill X. Declaración PRISMA: una propuesta para mejorar la publicación de revisiones sistemáticas y metaanálisis. Medicina Clínica. 2010;135(11), 507–511. 10.1016/j.medcli.2010.01.015
Da Costa Santos C, de Mattos Pimenta C, Cucce Nobre M. The PICO strategy for the research question construction and evidence search. Rev Latino-Am Enfermagem. 2007;15(3), 508–511. 10.1590/s0104-11692007000300023
Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M. Reliability of the PEDro scale for rating quality of randomized controlled trials. Phys Ther. 2003; 83(8):713-21. https://doi.org/10.1093/ptj/83.8.713
Jiménez Morgan S, Hernández Elizondo J. Efecto del ejercicio sobre la fatiga asociada al cáncer de mama en mujeres: meta-análisis de ensayos clínicos controlados aleatorizados. Journal of Sport and Health Research. 2017; 9(3): 285-290. https://www.kerwa.ucr.ac.cr/handle/10669/79173
Kessels E, Husson O, M van C. The effect of exercise on cancer-related fatigue in cancer survivors: a systematic review and meta-analysis. Neuropsychiatric Disease and Treatment. 2018;14:479-494. 10.2147/NDT.S150464
Mustian M, Alfano M, Heckler C, Kleckner A, Kleckner I, Leach C, et al. Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue A Meta-analysis. JAMA Oncol. 2017; 3(7). 10.1001/jamaoncol.2016.6914
Nakano J, Hashizume K, Fukushima T, Ueno K, Matsuura E, Ikio Y, et al. Effects of Aerobic and Resistance Exercises on Physical Symptoms in Cancer Patients: A Meta-analysis. Integrative Cancer Therapies. 2018; 17(4):1048-1058. https://pubmed.ncbi.nlm.nih.gov/30352523/
Dennett M, Peiris C, Shields N, Prendergast L, Taylora N. Moderate-intensity exercise reduces fatigue and improves mobility in cancer survivors: a systematic review and meta-regression. J Physiother. 2016; 62(2):68–82. 10.1016/j.jphys.2016.02.012
Buffart M, Kalter J, Sweegers G, Courneya K, Newton R, Aaronson N. et al. Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs. Cancer Treat Reviews. 2017; 52:91–104. 10.1016/j.ctrv.2016.11.010
Adamsen L, Quis M, Andersen C, et al. Effect of a multimodal high intensity exercise intervention in cancer patients undergoing chemotherapy: randomized controlled trial. BMJ. 2009; 339(b3410):1-11. 10.1136/bmj.b3410
Schmidt E, Wiskemann J, Armbrust P, et al. Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: A randomized controlled trial. IJC. 2015;137(2): 471–480. 10.1002/ijc.29383
Tian L, Lu J, Lin L. Effects of aerobic exercise on cancer-related fatigue: a meta-analysis of randomized controlled trials. Springer. 2016;24(2):969-983. 10.1007/s00520-015-2953-9
Meneses E, González E, Correa E, Schmidt Río J, Ramírez Vélez R. Efectividad del ejercicio físico en la fatiga de pacientes con cáncer durante el tratamiento activo: revisión sistemática y metaanálisis. Cad. Saúde Pública. 2015; 31(4):667-681. 10.1590/0102-311X00114414
Kelley A, Kelley S. Exercise and cancer-related fatigue in adults: a systematic review of previous systematic reviews with meta-analyses Exercise and cancer-related fatigue in adults: a systematic review of previous systematic reviews with meta-analyses. BMC Cancer. 2017; 17:693. 10.1186/s12885-017-3687-5
Van Vulpen, J, Peeters P, Velthuis M, van der Wall E, May A. Effects of physical exercise during adjuvant breast cancer treatment on physical and psychosocial dimensions of cancer-related fatigue: a meta-analy. Maturitas. 2016; 85:104-111. 10.1016/j.maturitas.2015.12.007
Zou L, Yang L, He X, Sun M, Xu JJ. Effects of aerobic exercise on cancer-related fatigue in breast cancer patients receiving chemotherapy: a meta-analysis. Tumour Biol. 2014;35(6): 5659-5667. 10.1007/s13277-014-1749-8
Moseley AM, Herbert RD, Sherrington C. Evidence for physiotherapy practice: a survey of the Physiotherapy Evidence Database (PEDro). Aust J Physiother. 2002;48(1):43-9. 10.1016/S0004-9514(14)60281-6
Brown J, Huedo T, Pescatello L, Pescatello Sh, Ferrer R; Johnson B. Effectiveness of exercise interventions in modulating in cancer-related fatigue among adult cancer survivors: a meta-analysis. Cancer Epidemiol Biomarkers Prev. 2011; 20(1):123-133. 10.1158/1055-9965.EPI-10-0988
Cramp F, Byron J. Exersice for the management of cancer – related fatigue in adults. Cochrane Database Syst Rev. 2012; 11(CD006145). 10.1002/14651858.CD006145.pub3
Govindbhai J, Bhise A. Effect of Aerobic Exercise on Cancer-related Fatigue. IJPC.2017;23(4): 355-361. 10.4103/IJPC.IJPC_65_17
Kangas M, Bovbjerg D, Montgomery G. Cancer-related fatigue: a systematic and meta-analytical review of nondrug therapies for cancer patients. Psychol Bull 2008; 134(5):700-741. 10.1037/a0012825
Velthuis M, Agasi-Idenburg S, Aufdemkampe G, Wittink HM. The effect of physical exercise on cancer-related fatigue during cancer treatment: a meta-analysis of randomised controlled trials. Clin Oncol (R Coll Radiol). 2010;22(3):208-221. 10.1016/j.clon.2009.12.005
Jemal A, Siegel R, Ward E, Hao Y, Jiaquan Xu, Thun MJ. Estadísticas de cáncer. CA Cancer J Clin. 2009;59(4):225-24. 10.3322/caac.20006
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