Cervicofacial cellulitis and its association with systemic diseases as a mortality factor, report of a clinical case
DOI:
https://doi.org/10.53732/rccsalud/2025.e7202Keywords:
cellulite, ludwig’s angina, diabetes mellitusAbstract
Odontogenic infections represent a reason for hospital admission in maxillofacial surgery, with a low mortality rate. However, some systemic pathologies increase the risk of infectious process exacerbation turning them into an emergency. This case report tries to show the relationship between cervicofacial infections and systemic diseases. We present a case of a 70-year-old patient admitted to the Hospital Dr. Adolfo Prince Lara Puerto Cabello- Venezuela with a diagnosis of Ludwig's Angina, which was drained in the operating room and transferred to the ICU. The patient was diagnosed in hospital with diabetes mellitus among other systemic diseases, so her evolution was unfavorable and she remained in the ICU and died of complications such as mediastinitis and pulmonary thromboembolism. We have shown the high complexity of the management of odontogenic infections in patients with systemic pathologies due to the faster and more severe progression of the infectious picture than in healthy patients.
References
Lin QL, Du HL, Xiong HY, Li B, Liu J, Xing XH. Characteristics and outcomes of Ludwig’s angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients. J Dent Sci. 2020;15(4):445-450. https://doi.org/10.1016/j.jds.2019.10.004
Jevon P, Abdelrahman A, Pigadas N. Management of odontogenic infections and sepsis: an update. Br Dent J. 2020 Sep;229(6):363-370. https://doi.org/10.1038/s41415-020-2114-5
Bertossi D, Barone A, Lurlaro A, Marconcini S, De Santis D, Finotti M, et al. Odontogenic Orofacial Infections. JCS. 2017;28(1):197-202. https://doi.org/10.1097/SCS.0000000000003250
Flynn T. Principles of management of odontogenic infections. In Miloro M, Ghali GE, Larsen P, Waite P (eds) Peterson’s principles of oral and maxillofacial surgery. 3rd ed. Beijing: PMPH, 2012.
Plaza Mayor G, Martínez San Millan J, Martinez Vidal A. Is conservative treatment of deep neck space infections appropriate?. Head Neck 2001;23(2):126–133. https://doi.org/10.1002/1097-0347(200102)23:2<126::AID-HED1007>3.0.CO;2-N
Guzmán-Letelier M, Crisosto-Jara C, Diaz-Ricouz C, Peñarrocha-Diago M, Peñarrocha-Oltra D. Severe odontogenic infection: An emergency. Case report. J Clin Exp Dent. 2017;9(2): e319-24. https://doi.org/10.4317/jced.53308
Gholami M, Mohammadi H, Amiri N, Khalife H. Key factors of odontogenic infections requiring hospitalization: A retrospective study of 102 cases. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2017;29:395–399. http://dx.doi.org/10.1016/j.ajoms.2017.03.016
Saifeldeen K, Evans R. Ludwig’s angina. Emerg Med J 2004; 21(2):242–243. http://dx.doi.org/10.1136/emj.2003.012336
Zamiri BA, Hashemi SB, Hashemi SH, Rafiee ZC, Ehsani S. Prevalence of Odontogenic Deep Head and Neck Spaces Infection and its Correlation with Length of Hospital Stay. Shiraz Univ Dent J. 2012;13(1):29-35. https://applications.emro.who.int/imemrf/J_Dent_Shiraz_Univ_Med_Sci/J_Dent_Shiraz_Univ_Med_Sci_2012_13_1_29_35.pdf
Umeda M, Minamikawa T, Komatsubara H, Shibuya Y, Yokoo S, Komori T. Necrotizing fasciitis caused by dental infection: a retrospective analysis of 9 cases and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(3):283-90. https://doi.org/10.1067/moe.2003.85
Grillo R, Borba A, Brozoski M, Moreira S, Silva Y, Naclério M. Evolution of the treatment of severe odontogenic infections over 50 years: A comprehensive review. JTUMED. 2023; 18(2):225-233. https://doi.org/10.1016/j.jtumed.2022.08.008
Kim MK, Nalliah RP, Lee MK, Allareddy V. Factors associated with length of stay and hospital charges for patients hospitalized with mouth cellulitis. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 2012;113(1):21-8. https://doi.org/10.1016/j.tripleo.2011.01.012
Jiménez Y, Bagán JV, Murillo J, Poveda R. Odontogenic infections. Complications. Systemic manifestations. Med Oral Patol Oral Cir Bucal. 2004; 9:143-7,139-43. https://pubmed.ncbi.nlm.nih.gov/15580132/
WHO Scientific Group of Immunodeficiency. Immunodeficiency: report of a WHO scientific group. World Health Organ Tech Rep Ser 1978;(630):3-80.
Kamat RD, Dhupar V, Akkara F, Shetye O. A comparative analysis of odontogenic maxillofacial infections in diabetic and nondiabetic patients: an institutional study. J Korean Assoc Oral Maxillofac Surg. 2015;41(4):176-80. https://doi.org/10.5125/jkaoms.2015.41.4.176
Golaszewski J, Muñoz R, Barazarte D, Maldonado A, Pulgar, Pérez J. A Fifteen Year Retrospective Study of Odontogenic Maxillofacial Infection in a Venezuelan Public Hospital. Res Rep Oral Maxillofac Surg. 2020;4(1):032. https://doi.org/10.23937/2643-3907/1710032
Martíne P, Pinacho P, Friedlander E, Martin C, Scola B. Peritonsillar and Deep neck infections: a review of 330 cases. Braz J Otorhinolaryngol. 2018;84(3):305-10. https://doi.org/10.1016/j.bjorl.2017.03.008
Weise H, Naros A, Weise C, Reinert S, Hoefert S. Severe odontogenic infections with septic progress – a constant and increasing challenge: a retrospective analysis. BMC Oral Health. 2019;19:173- 179. https://doi.org/10.1186/s12903-019-0866-6
Huang TT, Tseng FY, Liu TC, Hsu CJ, Chen YS. Deep neck infection in diabetic patients: Comparison of clinical picture and outcomes with nondiabetic patients. Otolaryngol Head Neck Surg. 2005;132(6):943-947. https://doi.org/10.1016/j.otohns.2005.01.035
Botha A, Jacobs F, Postma C. Retrospective analysis of etiology and comorbid diseases associated with Ludwig's Angina. Ann Maxillofac Surg. 2015;5(2):168-173. https://doi.org/10.4103/2231-0746.175758
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